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PMID: 87 Lima QueirozAZhangBComstockDEHaoYErikssonMHydbringPet al

All animal experiments were approved by the Animal Ethics Committee of Qiqihar Medical University (Approval No.: 2022401)

87 Moreover, IL-6 can promote the secretion of various acute-phase proteins such as CRP, hepcidin, fibrinogen, thrombopoietin, complement C3, and ferritin in hepatocytes

To further explore the function of Grx1 in macrophages in the regulation of acute lung injury pathogenesis in vivo, mice with conditional macrophage-specific genetic deletion of Grx1 (Grx1 fl/fl LysM cre ) and their wild-type littermate controls (Grx1 fl/fl ) were generated