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In a DPPH free radical clearance assay, compound 95 and its derivatives exhibited substantial antioxidant activity, with average IC 50 values of 38.40 and 36.53 g/mL, respectively

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Oxidative stress has been suggested to play a role in glaucoma pathogenesis

Other enzymes, such as the transcriptional regulator PhoP, and Glutamine synthetase are also included