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[5] Use of Lipo-C Injection is contraindicated in patients with known hypersensitivity to methionine, choline salts, carnitine, dexpanthenol, or any formulation excipients, as well as in individuals with severe hepatic failure in whom augmented methionine intake could precipitate hypermethioninemia and encephalopathy

The intestinal microbiota-dependent production of TMA/TMAO from L-carnitine was significantly decreased following meldonium treatment

[15] If a scheduled injection is missed, the patient should administer the dose as soon as remembered unless it is within 24 hours of the next scheduled dose, in which case the missed dose is omitted to prevent overlap