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The field of gliomas treatment still confronts with many obstacles, including chemotherapy resistance, tumor stem cells, and the tumor microenvironment[7, 8]

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Moreover, studies in neonatal porcine and adult human IEC lines have indicated that glutamine also promotes growth through augmenting the effects of growth factors, including insulin-like growth factor 1 and epidermal growth factor (108, 111113)

2.1.2 Aldosterone and salt infusion after unilateral nephrectomy (H 2 FPEF score 2) Initially described in rats, the combination of aldosterone infusion, unilateral nephrectomy and 1% sodium chloride (NaCl) loading induces blood pressure elevation, concentric LV hypertrophy with diastolic dysfunction and pulmonary congestion in both C57BL/6 and FB/N mice (Tanaka et al., 2016