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Louis, which hasnt gotten enough regard, shows that high protein intake, and this is shown both in mice and in people, will add to inflammation of the body, and at least in the mice models, promote atherosclerosis. And in fact, the leucine, as you mentioned, Howie, thats the essential amino acid

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However, the interesting part of this study mentioned how as the animals aged there was no clear reduction in longevity despite the obesity that developed, but when these animals were placed on a low-fat diet, lifespan increased by 30%

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