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Nat Commun 16 , 2716 (2025)

GPX4 positivity was significantly correlated with age ( P = 0.0292), and bone marrow involvement ( P = 0.0406) (Table 2)

1g and Extended Data Fig

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Although iron chelators such as deferoxamine (DFO) and deferiprone (DFP) have been shown to reduce ferroptosis-mediated damage in other diseases, they have not been well-studied in diabetes in human subjects