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Investigators are particularly interested in determining the mechanisms by which effects observed in murine models relate to broader mammalian metabolic regulation, and whether different experimental conditions (young vs aged models, healthy vs metabolically compromised states) show differential responses to NNMT inhibition

doi: 10.1523/JNEUROSCI.1160-19.2019 44 DehestaniM.KozarevaV.BlauwendraatC.FraenkelE.GasserT.BansalV

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CJC-1295 with DAC Addition of a maleimide arm (Drug Affinity Complex) that binds covalently to serum albumin

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