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However, several functions were expressed at very low levels in both BWS and nonBWS hepatocytes, including carnitine transporters, glycogen metabolism, lipogenesis, lipid mobilization, peroxisomal membrane and biogenesis, and synthesis of lipid precursors (Supplementary Fig

Cells were subsequently lysed using a suitable lysis solution including protease and phosphatase inhibitors to avert protein breakdown and maintain enzymatic activity

Skin tests, in particular, are considered the gold standard for diagnosing allergic disorders

In this study, AC effects were compared to that of pioglitazone, an insulin sensitizer acting by activation of peroxisome proliferator-activated receptor gamma (PPAR)

Briefly, C18 columns were activated by washing once with 400 L of acetonitrile (Fisher Scientific) and twice with 400 L of 0.1% formic acid (Thermo Scientific) in water solution, LCMS grade (Thermo Scientific)