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Goings on About Town: Deborah Remington. The New Yorker , May, 2021

At molecular level induction of hypertrophy associated genes are triggered by the DOX treatment which are alpha myosin heavy chain, ventricular myosin light chain-2, and atrial natriuretic peptide genes [60]

There are also genetic predispositions that render certain individuals susceptible to developing autoimmune diseases (83) and even after Epstein-Barr virus (EBV) infection (84), such as human leukocyte antigen (HLA) variants (84, 85) that have experienced selective pressures whilst co-evolving with pathogens (86, 87)

UV exposure, pollution, smoking, and hormonal fluctuations can all contribute to collagen loss

Conversely, expressed mutant Parkin results in increased levels of carbonyls, peroxidation of lipids, and nitrated proteins (Hyun et al