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Yes when taken responsibly, they are among the safest and most researched antioxidants in the world

doi: 10.1046/J.1365-2249.2001.01453.X 157 WuZ,MMacPheeI,GOliveiraD

Patients who present after 24 hours may already have signs of liver failure-hepatic tenderness, jaundice, impaired consciousness, asterixis, foetor hepaticus, and haemorrhage