These conclusions deepen the understanding of ASD pathogenesis and provide critical evidence for clinical applications of microbiota-targeted therapies, holding significant scientific and societal value

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however, mice lacking Slc30a10 specifically in neurons, the liver, or the small intestine exhibit minimal alterations in Mn levels 38,39 , although endoderm-specific Slc30a10 knockout mice exhibit changes in systemic Mn levels that are similar to global Slc30a10 knockout mice 38
Should I change my supplement regimen if exposed to toxic substances