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In the gastric cancer TME, L-Kynurenine (L-KYN), which is a metabolite derived from tryptophan, was documented to provoke lipid peroxidation thereby induce ferroptosis in NK cells [135]

Sun B, Zhou L, Wen Y, Wang C, Baer TM, Pera RR, et al

Mitochondria-targeted pentacyclic triterpenoid carbon dots for selective cancer cell destruction via inducing autophagy, apoptosis, as well as ferroptosis

Here the data from yeast one-hybrid and dual luciferase assays indicated that MrMYB1.1 directly bind to the MrGST1 promoter and activated the transcriptional activity of the MrGST1 promoter, and the transcriptional activity of MrGST1 promoter was further up-regulated via the cooperation between MrMYB1.1 and MrbHLH1

Chemical disruption of the pyroptotic pore-forming protein gasdermin d inhibits inflammatory cell death and sepsis