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The decoction may enhance mucin secretion and diminish inflammation, by suppressing the NF-B pathway, both essential for relieving DED [93]

In individuals with IBD, proinflammatory cytokines downregulate OCTN2 through the PPAR/RXR pathway, resulting in reduced carnitine uptake by intestinal epithelial cells that leads to the dysfunction of intestinal regeneration and repair and further deterioration of IBD [232]