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Author contributions SCR and JH conceived the paper

Specificity of the DCFDA-based ROS assay was confirmed using HO as a positive control and catalase as a negative control (Figure S1)

5lm and Supplementary Fig

Continuous inflammation caused by UV radiation or other damage can further promote oxidative stress, stimulate the proliferation of skin immunosuppressive cells, and produce early cancer cell growth factors, which damage cellular biomolecules and accelerate skin aging