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Initially, System Xc- facilitates cystine uptake through the interaction of its subunits SLC7A11 and SLC3A2 ( In the skin microenvironment, the level of cysteine is strictly regulated

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Following treatment with 0.5 mg/mL LPC, an initial increase in GFAP+ expression is observed over a 72-h period when compared to that of untreated slices, but with further time in culture, no difference in GFAP+ expression is seen between untreated and LPC-treated slices

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