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Studies in mouse models of NAFLD and obesity, diet-induced or not, support the results seen in human studies with repression of Agxt expression 10, 52

These include N,N -bis(2-hydroxybenzyl)ethylenediamine- N,N -diacetic acid (HBED), the hydrazones pyridoxal isonicotinoyl hydrazone (PIH) and salicylaldehyde isonicotinoyl hydrazone (SIH), desferrithiocin, and, 2,3-dihydrobenzoic acid