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Also known as cobalamin, B12 is a powerhouse that helps keep your brain and nervous system healthy, produces red blood cells, and even plays a part in creating DNA

Lloyd-Turner, S., Peters, J., & Harrison, L

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Before treatment, clients often experience low energy, difficulty losing weight, or sluggish metabolism

The predicted inhibitor-binding mode of 1j with an orientation and conformation that favors most negative docking score when superimposed with the endogenous substrate NCA of the NNMT enzyme indicated that the analog binds consistent with the binding mode of NCA, i.e., the N1-atom of both ligands aligned almost identical, conferring similar molecular interactions with key residues within the active site of the enzyme