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Similar patterns have been reported previously 41,87

14 In terms of brain organoids, researchers have successfully introduced mutant genes associated with Alzheimer's disease, brain development abnormalities, autism, and other diseases, such as APP, MECP2, and CHD8, into iPSCs to construct mutant brain organoids for observing pathological features such as A deposition, neural network development disorders, and axon guidance disorders

Interestingly, miR-26 better reduced intima-media thickness (IMT) than PCSK9 or CT-1 knockout

Elrod et al

This may be the earliest proof of the underlying mechanism of ferroptosis in hemorrhagic stroke