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Description

Inflammation accelerates copper-mediated cytotoxicity through induction of six-transmembrane epithelial antigens of prostate 4 expression

Future studies are needed to tackle the molecular mechanisms mediating these cell-type specific rearrangements

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The H-bond network is only observed for OCTN2 in the occluded conformation and is absent in the inward-facing conformation, supporting that the network helps to stabilise a kinked conformation of TM11 that packs against TM2