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It is also a natural osmoprotectant, meaning that it attracts water away from the protein surface and thus protects them from denaturation and increases their thermodynamic stability

Kale OE, Akinpelu OB, Bakare AA, Yusuf FO, Gomba R, Araka DC, Ogundare TO, Okolie AC, Adebawo O, Odutola O

The RNAprotein complex was captured by streptavidin-couped Dynabeads (Thermo, 65606D) (room temperature, 30 min), washed with ice-cold 1 TENT buffer, mixed with 1 Laemmli sample buffer and heated for 10 min at 95 C for immunoblot analysis using anti-YBX1 antibody (ABclonal, A3534)

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Hear Res 395:108019 Della Porta A, Bornstein K, Coye A, Montrief T, Long B, Parris MA (2020) Acute chloroquine and hydroxychloroquine toxicity: a review for emergency clinicians