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Overexpression of MT1G inhibits the proliferation, migration, and invasion functions of GC cells, reduces SOD and GSH content, increases MDA content, cause the mitochondrial membrane potential to weaken and promote the transformation of JC-1 aggregates to JC-1 monomer, increases Fe 2+ , affects ROS, and reduces GPX4 and SLC7A11 protein expression, promoting ferroptosis

The hPL is collected from activated healthy human donor platelets with abundant growth factors, thereby minimizing the risks of xenogeneic immune responses, zoonotic transmission, and the ethical issues associated with animal-derived serum (Gstraunthaler, 2003

Clinical review: oxygen as a signaling molecule

doi: 10.3233/JAD-190083, 147

enfin, Ibrahim et al