chac1 glutathione A scheme of the mechanism of degradation of enhancing journal club - Kidney International
journal club Kidney International Glutathione (GSH) depletion by ChaC1 results in a more oxidizing Download Scientific Diagram CHAC1 degradation of glutathione enhances cystine starvation induced necroptosis and ferroptosis in human triple negative breast cancer cells via the GCN2 eIF2 ATF4 pathway Oncotarget Dysregulated lipids homeostasis disrupts CHAC1 mediated ferroptosis driving fibroblast growth factor receptor tyrosine kinase inhibitor AZD4547 resistance in gastric cancer ScienceDirect Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv
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