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It typically presents in middle-aged adults with fatigue, weight loss, and massive splenomegaly

It also failed to trigger the migration of CD8 + and CD4 + T cells, while only slightly inducing the migration of CD19 + B cells

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Its continental crust is heterogeneous and consists of a crystalline basement of the dipilto patuca microblock (DPM) and a dense crust formed by the mesquito composite oceanic terrane (MCOT)