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Withdrawal of immunosuppression Withdrawal of immunosuppressive therapy has been explored in a select subset of AIH, albeit with variable success rates [145,146,147,148,149,150,151,152]

The ability of IL-1 to induce chondrocyte catabolism [121] has been well known for a long time, but it is only recently that IL-1 has been shown to disrupt chondrocyte iron homeostasis [117] and trigger chondrocyte ferroptosis [22, 122]