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Furthermore, the findings of a preclinical study examining the efficacy of recombinant human IL-7 (rhIL-7) as a lymphostimulating intervention in sepsis revealed that the ex vivo administration of rhIL-7 to patients cells resulted in a noteworthy enhancement of lymphocyte functionality in various aspects, including the proliferation of CD4(+) and CD8(+) lymphocytes, the production of IFN-, the phosphorylation of STAT5, and the induction of B cell lymphoma 2 following stimulation (Venet et al., 2012)

BMC Neurol 21:381

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Nucleic Acids Res 45:98102 Vera M, Torramade-Moix S, Martin-Rodriguez S, Cases A, Cruzado JM, Rivera J, Escolar G, Palomo M, Diaz-Ricart M (2018) Antioxidant and anti-inflammatory strategies based on the potentiation of glutathione peroxidase activity prevent endothelial dysfunction in chronic kidney disease

JoyceJMMercierLJStokoeMLaPLBellTBatyckyJMet al