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Carnitine-dependent fatty acid oxidation is mediated by the sequential action of carnitine palmitoyltransferase 1 (CPT1), carnitine acylcarnitine translocase (CACT), and carnitine palmitoyltransferase 2 (CPT2), and it provides long-chain acyl-CoA to the -oxidation spiral which produces acetyl-CoA, NADH, and FADH2

This guide/article is provided for informational context regarding standard laboratory in-vitro/in-vivo research procedures only, and does not constitute medical, clinical, veterinary guidance or treatment advice.

Additionally, two small studies in participants presenting with antiretroviral-induced neuropathy found significant reduction in subjects' mean pain intensity with oral ALCAR (1-3 g/day) for 4 to 24 weeks, but no effect on objective neurophysiological parameters was found (82, 83)