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[34] Notably, zoledronic acid has been previously associated with lifespan extension in progeroid mice

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Based on the predicted results from JASPAR, ChIP assays were conducted to confirm the binding region of Np63 on gene enhancer or promoter in HCC95 cells using the ChIP-IT Kit (53009, Active Motif, USA)

Notably, the truncated isoform TrkB T1 is regarded as the dominant negative form and may thereby suppress the neurotrophic activity of BDNF (Vidaurre et al., 2012)

TIME RELEASE DELIVERY SYSTEM: Formulated with a gradual release mechanism to allow nutrients to be delivered over time