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Description

The th17 pathway in cystic fibrosis lung disease

DOI:10.1016/j.cell.2004.12.041 72

Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor

Apo-SOD1 is first imported into the IMS, where it binds to CCS for metalation, ultimately forming mature SOD1 that performs antioxidative functions by scavenging superoxide radicals (155,156)