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A study conducted among 100 women showed that 26 pregnant women with preeclampsia had a significantly lower abundance of Prevotella , Porphyromonas , Varibaculum , and Lactobacillus than pregnant women without this complication (Huang et al., 2021)

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Thus, a lot of onus is on refining animal models and improving patient stratification to consider individual genetic and phenotypic variations in neurological diseases for the success of NP-based systems in clinical practice