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Overall, the purpose of this review is analyze and review the latest studies aimed on the multiple roles of MTs in metabolic disorders, possible use of MTs as obesity and diabetes biomarkers and the role of MTs in cardioprotection during diabetes progression

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Treatment using surgical excision alone has a recurrence rate of up to 70%, with tumour regrowth usually occurring within the first six months after surgery (Hendrick et al., 1994), but preoperative or postoperative radiation therapy significantly decreases recurrence rates and prolongs remission times (Cronin et al., 1998

[78] Soil that is deficient in cobalt may result in B 12 deficiency, and B 12 injections or cobalt supplementation may be required for livestock