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A purified membrane protein from akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

In these studies, the authors determined that the induction of long-term depression (LTD) is enhanced by blocking Glu uptake that then activates extrasynaptically located N -methyl d-aspartate receptor subtype 2B (NR2B/GRIN2B) receptors, whereas the de-potentiation phenomenon requires activation of N -methyl d-aspartate receptor subtype 2A (NR2A/GRIN2A) receptors

Free Radic Biol Med (2007) 42(11):166170

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