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In addition, there was a time-dependent increase of H 2 O 2 content, along with the high expression of p53 and p21 in primary hepatocytes of CCl 4 -induced rats (Supplementary Fig

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In addition, the following exclusion criteria were applied: Young individuals with previously diagnosed pathologies, generating arrhythmias or oxidative stress including: i) pathologies that cause secondary arrhythmias such as hyperthyroidism, myxedema, anemia, hypotension, hypoglycemia, febrile syndrome, myocarditis, orpheochromocytoma