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doi: 10.3389/fnut.2026.1830797 Received 14 March 2026 Revised 03 April 2026 Accepted 03 April 2026 Published 28 April 2026 Volume 13 - 2026 Edited by Srutee Rout, Indian Institute of Technology, Kharagpur, India Reviewed by Mukul Machhindra Barwant, Sanjivani Arts, Commerce, and Science College, India Ahmad Rabbani, United Arab Emirates University, United Arab Emirates Updates Copyright 2026 Alblaji

In some situations, injections might not be the best course of action

Among patients with early TNBC, as in the KEYNOTE-522 trial, neoadjuvant pembrolizumab plus chemotherapy, followed by adjuvant pembrolizumab after surgery, resulted in significantly higher pCR, especially longer EFS and os than neoadjuvant chemotherapy alone

This process, primarily mediated by mitophagy, not only supports metabolic plasticity and reprogramming in PDAC cells but also fosters tumorigenesis and confers resistance to apoptosis [57]