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Third, hyperhomocysteinemia detected both under basal conditions and after a methionine challenge (approximately 50% of patients), which might be partially explained by a saturation of the transsulfuration pathway caused by dietary methionine excess

Azhar S, Cao L, Reaven E

Kotas, M

Mic B12 dosage typically ranges from 500 to 2,500 micrograms per injection, administered weekly or monthly depending on clinical indication and baseline B12 status