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Immune cells of the CNS are primarily compartmentalized within the meninges, choroid plexus, and parenchyma, each with distinct structures and barriers that regulate molecular exchange and immune accessibility

The deficiencies are mainly characterized by neurotransmitter dysfunction, with or without HPA, which nowadays is typically identified at the newborn screening [61]

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Adult male C57BL/6 mice on a 60% kcal-from-fat high-fat diet received intraperitoneal or oral 5-Amino-1MQ at amounts in the milligram-per-kilogram range or vehicle, over an 11-day treatment period in the published protocol