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Instead, it primarily led to cell cycle arrest in response to BET inhibitor treatment in solid cancer cells

The encapsulation of dexamethasone in PLGA NPs allows for controlled release and targeted delivery, reducing systemic side effects and enhancing efficacy (169)

Importantly, these data are reflected by results from human studies demonstrating lower risk of colon5,7 as well as lung31 cancer in Gilbert syndrome subjects

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For instance, for a MASLD patient characterized by enrichment of a specific pathogen and lack of SCFAs, the treatment plan might include phages targeting that pathogen, supplementation with specific butyrate-producing strains, and dietary guidance rich in fermentable fibers