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The malonyl-CoA product is further converted by FASN to long-chain fatty acids

Breast cancer development and progression: risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis

A Shimadzu liquid chromatography system (Japan) was employed, consisting of a high-pressure pump (LC-30AD), online degasser (DGU-20A5R), autosampler (SIL-30AC), and column oven (CTO-30 A), all controlled by a system controller (CBM-20 A)

2013 Apr 3;309(13):135967

The mechanism involves IGF2BP2 enhancing the m6A modification and stability of ALDOA mRNA, leading to increased ALDOA expression levels and lactate production, which subsequently promotes H3K18la and accelerates liver fibrosis (91)