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recently applied thiol-ene chemistry in their development of activity-based probes (ABPs) to target DUBs with the additional advantage of control over initiation of the enzyme-probe reaction (Taylor et al., Figure 13B)

Inhibitory effects of harpagoside on TNF--induced pro-inflammatory adipokine expression through PPAR- activation in 3T3-L1 adipocytes

The researchers believed an MMA level of 350 nmol/l could be indicative of a functional B12 deficiency

GRM7 variants associated with age-related hearing loss based on auditory perception

This shift in perspective also opens new challenges for computational and experimental drug discovery