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Recent studies done on animals found that high fiber diets helped in mitigating hippocampal inflammation following abdominal radiation, while preserving goblet cell integrity and tight junction protein expression (Church et al., 2023

103,104,105 Notably, a previous immunohistochemical study showed that the infiltration of CD68 + macrophages in OSF tissue increased, and the level of infiltration was positively correlated with the aggravation of pathological stage