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Some physicians will authorise patients to receive injections more frequently than the recommended regimen (see Box), but many will not

Activation of these receptors enhances burst firing in dopaminergic neurons, increases dopamine release in the nucleus accumbens, thereby forming rewarding signals for external stimuli such as nicotine ( 5 , 3 , and 4 subtypes similarly play negative regulatory roles in nicotine uptake and aversive effects (Sheffield et al., 2000)

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However, many small- and medium-sized cities in Brazil and the Global South lack the institutional capacity to effectively engage residents in climate governance