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the major mechanisms by which the drug is cleaved from the antibody include hydrolysis in the acidic pH of the lysosomes (hydrazones, acetals, and cis-aconitate-like amides), peptide cleavage by lysosomal enzymes (the cathepsins and other lysosomal enzymes), and reduction of disulfides

The counterfactual here matters for current patients: how many people today are depleted without knowing it because redox panels still aren't part of routine metabolic screening

Implementation and Governance Effective implementation of anaemia control programs requires tailored, multi-sectorial strategies and ongoing monitoring

(2013) The impact of oxidative stress in thiamine deficiency: a multifactorial targeting issue

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