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The existence of a direct interaction between levodopa and the outer membrane proteins of HP was suggested by one in vitro study where levodopa concentration was reduced in a time- and HP density-dependent manner when exposed to HP, and pre-incubation of levodopa with HP showed significantly reduced bacterial adhesion to gastric epithelial cells [58]

[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Svahn AJ, et al

Cells were grown for 24 h in the exetainers, and the gas in the headspace of the exetainers was collected for analysis

Anal Bioanal Chem (2004) 378:1839

8523, revised 1996), approved by the Guangxi Medical University Animal Ethics Committee, and carried out in compliance with the ARRIVE guidelines ( Pathogen-free inbred male SpragueDawley rats (220250 g) were obtained from the Experimental Laboratory Animal Centre of Guangxi Medical University (Nanning, China)