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205 SIRT3 functions as a deacetylase, regulating mitochondrial acetylation levels, which are closely linked to metabolic processes such as OXPHOS, FAO, and the TCA cycle across various organs

However, unlike apoptosis [198,199,200], eryptosis probably cannot be regulated at the epigenetic, transcriptional, and translational levels

As a small molecule that mimics and potentiates HGF activity while maintaining oral bioavailability and blood-brain barrier penetration, Dihexa offers practical advantages over gene therapy or protein-based approaches for clinical translation

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