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Combined approach most effective

The results are calculated by evaluating the increase in OD per minute (slope) for unknowns against the slope for a Standard with known G-6-PD activity

Several independent studies have also shown that treatment with arimoclomol, a co-inducer of heat shock proteins, is protective against toxic mutant SOD1 aggregates, delays disease progression and improves motor function in SOD1 G93A mice (Kieran et al., 2004

NAC suppresses the oxidative stress level in EAAC1 KO mice, but not in GLAST KO mice We next examined the antioxidant effects of NAC in EAAC1 and GLAST KO mice