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PMID: 6149546, PMCID: PMC391955, DOI: 10.1073/pnas.81.20.6516

Moreover, non-targeted effects such as the abscopal (RIAE) and bystander effects (RIBE) can induce biological consequences, such as adaptive response, genomic instability and genetic susceptibility, to neighboring cells through signaling factors released by irradiated cells [124, 125]

Several studies have found that the use of the crude extract, purified, or recombinant molecules/proteins derived from helminths can produce similar anti-inflammatory effects as whole organisms [192-195]