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A gradient was as follows: 0.5 min the column was hold at 4% B, then linear increase from 1 to 15% B in 1 min, then to 40% B in 3 min, and to 100% B in 0.5 min, and hold at 100% B for 1 min

Statistical Analysis All results are statistically confirmed SPSS 13.0 (SPSS, United States) and expressed as mean SEM

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During off work hours (nights and weekends), roadway will be open to all traffic

Axfors et al., Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials, Nature, doi:10.1038/s41467-021-22446-z