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As anticipated, the dissection of apparent equilibria into elementary redox ones in biological thiol-disulfide systems reveals significant differences between reactions of apparently highly similar, covalently identical reactants, improving thus our understanding of redox homeostasis and providing new means to influence it

Furthermore, while the presence of do not eat me signals, such as CD47 and PD-L1, is known to regulate phagocytosis in other cellular contexts, their existence and role in ferroptotic cells remain largely uncharacterized

10.1016/j.drudis.2009.10.009 150 WangC.LiuY.FanY.LiX

Furthermore, Cryo-EM has advanced mechanism research in the structural pharmacology of Chinese medicine by enabling high-resolution analysis of active ingredient in complex with target proteins

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