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Strati P, Kantarjian HM, Thomas DA, O'Brien SM, Jabbour EJ, Quintas-Cardama A, Borthakur G , Faderl S, Ravandi F, Cortes JE

Nat Cell Biol (2018) 20(7):74554

Although the transport of small molecules from epithelial cells to fiber cells has been demonstrated, , the relative importance of this pathway in providing nutrients to the fiber cells, compared to transport directly across the surface membranes of superficial fiber cells, has not been determined

patient-related factors

prkn / // Sod2 +/+ and Sod2 // prkn +/+ mice were crossed to generate prkn // Sod2 offspring, which was interbred to produce the desired prkn / // Sod2 (bi-genic) mouse