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As a mitochondrial enzyme, HOT can strongly influence D -2HG availability by coupling iron metabolism with MYC gene activation, thereby indirectly affecting IDH2 activity (48)

Thymidine kinase 2 gene compound heterozygous mutation leads to mitochondrial DNA depletion syndrome-2: a case report

Additionally, DHA could suppress the activity of nuclear factor-B (NF-B) through the lipopolysaccharides (LPS) surface receptor (132)

GPx is a tetrameric enzyme with seleno-cysteine (SeC) as a cofactor in its active site

De plus, certaines lipases sont capables d'hydrolyser des phospholipides, des esters de cholestrol et mme parfois certains esters synthtiques