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With a special focus on chemokines CCL2 and CCL7, which facilitate macrophage chemotaxis and recruitment, ferroptosis enhances the expression of many inflammation-associated genes (102)

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Figure 2 2.1 The primary factor contributing to the deterioration in oocyte quality is the elevation in oxidative stress In women of advanced reproductive age, oocytes demonstrate elevated levels of reactive ROS as a consequence of mitochondrial dysfunction

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MEK and TAK1 contain the conserved cysteine residue corresponding to ERK2 (95)